Endocrinology/HormonesWithoutMuchPituitaryRole/GlucagonAndInsuliln/Insulin/ControlBasic/Meal
| When blood glucose is increased, negative feedback facilitates insulin (synthesis, secretion, and blood concentration). |
(Synthesis, secretion, and blood concentration of) Insulin decreases blood glucose.Insuliln has a certain (baseline) amount of synthesis, secretion, blood concentration, and blood glucose-increasing effect before meal.
① Subject had meal. Blood glucose is increased due to the meal. Insulin (synthesis, secretion, and blood concentration) decreases blood glucose.These are in the opposite direction (blue).
② Since these are in the opposite direction (blue), negative feedback facilitate (red) insulin (synthesis, secretion, and blood concentration). Because of this, the blood glucose-increasing effect of insulin strengthens, and the increase in blood glucose (red upward unfilled arrow) disappears (increased blood glucose decreases to the baseline).
Like, when room temperature is increased (summer), cooler (function) is increased, this also is blue→red negative feedback.
Challenge Quiz
Blood glucose is increased decreased due to the meal, insulin (synthesis, secretion, and blood concentration increases decreases blood glucose. Since these are in the same direction opposite direction , negative feedback inhibits facilitates insulin. Because of this, the initial transition dissapears and the blood glucose increases decreases (towards the baseline).
When blood glucose is increased, negative feedback inhibits facilitates insuliln (synthesis, secretion, and blood concentration).