Endocrinology/HormonesWithoutMuchPituitaryRole/GlucagonAndInsuliln/Insulin/ControlBasic/Fasting
| When blood glucose is decreased, negative feedback inhibits insuliln(synthesis, secretion, and blood concentration). |
(Synthesis, secretion, and blood concentration of) insuliln decreases blood glucose. Insuliln has a certain (baseline) amount of synthesis, secretion, blood concentration, and blood glucose-increasing effect before fasting.
① Subject had fasted. Blood glucose is decreased due to the fasting. Insuliln (synthesis, secretion, and blood concentration) decreases blood glucose. These are in the same direction (red).
② Since these are in the same direction (red), negative feedback inhibits (blue) insuliln (synthesis, secretion, and blood concentration). Because of this, the blood glucose-increasing effect of glucagon weakens, and the decrease in blood glucose (blue downward unfilled arrow) disappears (decreased blood glucose increases to the baseline).
Like, when room temperature is decreased (winter), cooler (function) is decreased, this is also red→blue negative feedback.
Challenge Quiz
Blood glucose is increased decreased due to the fasting, insuliln (synthesis, secretion, and blood concentration increases decreases blood glucose. Since these are in the same direction opposite direction , negative feedback inhibits facilitates insuliln. Because of this, the initial transition dissapears and the blood glucose increases decreases (towards the baseline).
When blood glucose is decreased, negative feedback facilitates inhibits insuliln (synthesis, secretion, and blood concentration).