Endocrinology/VasopressinADH/ControlToWaterIntake/basic
| With water intake, the (red→blue) negative feedback inhibits (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH). |
① Water intake decreases plasma osmolarity, and reabsorption (through the water channels, which are increased by vasopressin, ADH) decreases plasma osmolarity. These effects are in the same direction (red).
② Since these effects are in the same direction (red), negative feedback inhibits (blue) (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH). This decreases the number of water channels and the reabsorption of water. The plasma osmolarity-decreasing effect of the reabsorption decreases. This will lead to a reverse in the decreased plasma osmolarity, increasing it towards normal osmolarity.
Challenge Quiz
Water intake increases decreases plasma osmolarity, and reabsorption (through the water channels, which are increased by vasopressin, ADH) increases decreases plasma osmolarity. Since these effects are in the same opposite direction, negative feedback facilitates inhibits (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).