Endocrinology/VasopressinADH/ControlToSweating/basic
| With sweating, the (blue→red) negative feedback increases (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH). |
1st star (illustration): Subject sweated. With sweating, plasma osmolarity increases. (Synthesis, secretion, and concentration in blood of )vasopressin (ADH) (increases water channels. Water channels increase water reabsorption. Water reabsorption) decreases plasma osmolarity.
①(illustration): These are in the opposite direction (blue).
②(illustration): Since these are in the opposite direction (blue), negative feedback increases (red) (synthesis, secretion, and concentration in blood of vasopressin (ADH).
With the increase in (the synthesis, secretion, and concentration in blood of)vasopressin (ADH), (water channel-increasing effect is strengthened, and water channels are increased. With the increase in water channels, water reabsorption-increasing effect is strengthened, and water absorption is increased. With the increase in water reaborption), plasma osmolarity-decreasing effect is strengthened.
Because of this control, the increased plasma osmolarity decreases (towards that before sweating).
Namely, the initial change (the increase in plasma osmolarity) decreases (red upward unfilled arrow disappears).
Similar to cooler (function) being increased when room temperature is increased (summer), this also is blue→red negative feedback.
Challenge Quiz
Sweating increases decreases plasma osmolarity, and water reabsorption (through the water channels, which are increased by vasopressin, ADH) increases decreases plasma osmolarity. Since these effects are in the same opposite direction, negative feedback increases decreases (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).