Endocrinology/VasopressinADH/ControlToSweating/basic

POINT!

With sweating, the (blue→red) negative feedback increases (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).

① Sweating increases plasma osmolarity (concentrated, hypertonic), and water reabsorption (through the water channels, which are increased by vasopressin, ADH) decreases plasma osmolarity. These effects are in the opposite direction (blue).

② Since these effects are in the opposite direction (blue), negative feedback increases (red) (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH). This increases the number of water channels and the water reabsorption. The plasma osmolarity-decreasing effect of the water reabsorption becomes stronger. This will lead to a reverse in the increased plasma osmolarity (concentrated, hypertonic) produced by sweating, decreasing it towards normal (baseline, isotonic) osmolarity.

Challenge Quiz

1.

Sweating increases decreases  正解! plasma osmolarity, and water reabsorption (through the water channels, which are increased by vasopressin, ADH) increases decreases  正解! plasma osmolarity. Since these effects are in the same opposite  正解! direction, negative feedback increases decreases  正解! (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).