Endocrinology/HormonesWithoutMuchPituitaryRole/GlucagonAndInsuliln/Insulin/ControlBasic/Meal

POINT!

When blood glucose is increased, negative feedback facilitates insulin (synthesis, secretion, and blood concentration).

動画と音声での説明

(Synthesis, secretion, and blood concentration of) insulin decreases blood glucose. Insulin has a certain (baseline) amount of synthesis, secretion, blood concentration, and blood glucose-decreasing effect before meal.

① Subject had meal. Blood glucose is increased due to the meal. Insulin (synthesis, secretion, and blood concentration) decreases blood glucose.These are in the opposite direction (blue).

② Since these are in the opposite direction (blue), negative feedback facilitates (red) insulin (synthesis, secretion, and blood concentration). Because of this, the blood glucose-decreasing effect of insulin strengthens, and the increase in blood glucose (red upward unfilled arrow) disappears (increased blood glucose decreases to the baseline).

Like, when room temperature is increased (summer), cooler (function) is increased, this also is blue→red negative feedback.

Challenge Quiz

1.

Blood glucose is increased decreased  正解! due to the meal, insulin (synthesis, secretion, and blood concentration increases decreases  正解! blood glucose. Since these are in the same direction opposite direction  正解!, negative feedback inhibits facilitates  正解! insulin. Because of this, the initial transition dissapears and the blood glucose increases decreases  正解! (towards the baseline).

2.

When blood glucose is increased, negative feedback inhibits facilitates  正解! insuliln (synthesis, secretion, and blood concentration).