「SHolroydAtWeilCornellMedQatar/Endocrinology/VasopressinADH/EffectOfIncrease」の版間の差分
編集の要約なし |
編集の要約なし |
||
| 1行目: | 1行目: | ||
{{Point| With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels and water reabsorption increase. These decrease plasma osmolarity and urine volume, and increase urine osmolarity.}} | {{Point| With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels and water reabsorption increase. These decrease plasma osmolarity and urine volume, and also increase urine osmolarity.}} | ||
[[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | [[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | ||
| 5行目: | 5行目: | ||
<div class="avoid-page-break"> | <div class="avoid-page-break"> | ||
[[ファイル:ADHbaseline-Eng.jpg|left|500px]] | [[ファイル:ADHbaseline-Eng.jpg|left|500px]] | ||
[[メディア:ADHbaseline-Eng.mp4|video prior to | [[メディア:ADHbaseline-Eng.mp4|video prior to an increase in vasopressin (ADH)]]<br> | ||
Prior to vasopressin (ADH) increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and volumes. | Prior to vasopressin (ADH) increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and volumes. | ||
<br style="clear:both;" /> | <br style="clear:both;" /> | ||
| 12行目: | 12行目: | ||
<div class="avoid-page-break"> | <div class="avoid-page-break"> | ||
[[ファイル:ADHEffectOfIncreasing-2Eng.jpg|left|500px]] | [[ファイル:ADHEffectOfIncreasing-2Eng.jpg|left|500px]] | ||
[[メディア:ADHEffectOfIncreasing-2Eng.mp4|video just after | [[メディア:ADHEffectOfIncreasing-2Eng.mp4|video just after an increase in vasopressin (ADH)]]<br> | ||
Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) increases.<br> | Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) increases.<br> | ||
Step 2: The water channel-increasing effect of vasopressin (ADH) | Step 2: The water channel-increasing effect of vasopressin (ADH) becomes stronger, which increases the number of water channels. This increases the reabsorption of water by the kidney. | ||
<br style="clear:both;" /> | <br style="clear:both;" /> | ||
| 29行目: | 29行目: | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels in the kidney {~= | With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels in the kidney {~=increases~decreases} . | ||
//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), | With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), water reabsorption by the kidney {~=increases~decreases}. | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), | With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine volume {increases~=decreases}. | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), | With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine osmolarity {~=increases~decreases}. | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), | With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), plasma osmolarity {increases~=decreases}. | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
The effect of | The effect of increase in vasopressin (anti-diuretic hormone, ADH) is {uterine smooth muscle contration~=a decrease in plasma osmolarity}. | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
The effect of | The effect of increase in vasopressin (anti-diuretic hormone, ADH) is {an increase~=a decrease} in plasma osmolarity. | ||
</GIFT> | </GIFT> | ||
2019年8月31日 (土) 12:39時点における版
| With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels and water reabsorption increase. These decrease plasma osmolarity and urine volume, and also increase urine osmolarity. |
video prior to an increase in vasopressin (ADH)
Prior to vasopressin (ADH) increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and volumes.
video just after an increase in vasopressin (ADH)
Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) increases.
Step 2: The water channel-increasing effect of vasopressin (ADH) becomes stronger, which increases the number of water channels. This increases the reabsorption of water by the kidney.
video showing the changes in plasma and urine after the increase in vasopressin (ADH)
Step 3: The ratio of Na+ to water entering the plasma due to reabsorption decreases. This decreases plasma osmolarity (hypotonic). Because a lower ratio of Na+ to water leaves the tubule due to reabsorption, the fluid remaining in the tubule has a higher osmolarity (hypertonic). Also, with an increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes more concentrated (hypertonic) and lower in volume.
Challenge Quiz
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels in the kidney increases decreases .
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), water reabsorption by the kidney increases decreases .
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine volume increases decreases .
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine osmolarity increases decreases .
With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), plasma osmolarity increases decreases .
The effect of increase in vasopressin (anti-diuretic hormone, ADH) is uterine smooth muscle contration a decrease in plasma osmolarity .
The effect of increase in vasopressin (anti-diuretic hormone, ADH) is an increase a decrease in plasma osmolarity.