「Nervous system/overview of neurons/Crush syndrome/effect of hyperkalemia on cardiac muscle」の版間の差分
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When a muscle is crushed, K<sup>+</sup> in blood is {=increased~decreased}, and in cardiac muscle cells, diffusion of K<sup>+</sup> through K<sup>+</sup> channel is {=less~more}, resting membrane potential is {=less~more}, stability of the cell is {=less~more}, causing arrythmia. | When a muscle is crushed, K<sup>+</sup> in blood is {=increased~decreased}, and in cardiac muscle cells, diffusion of K<sup>+</sup> through K<sup>+</sup> channel is {=less~more}, resting membrane potential is {=less~more}, stability of the cell is {=less~more}, causing arrythmia. | ||
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2015年5月5日 (火) 09:15時点における版
When a muscle is crushed, K+ in blood is increased, and in cardiac muscle cells, diffusion of K+ through K+ channel is less, resting membrane potential is less, stability of the cell is less, causing arrythmia. |
Both the high intra-cellular potassium (K+) and low extra-cellular potassium (K+) bring about the difference, which is the driving force of the diffusion of potassium ion (K+) through channel. With more diffusion, the intracellular resting membrane negative potential increases, and with more intracellular resting membrane potential, the cell becomes more stable.
When the legs are compressed for a long time, such as in earthquake-destroyed buildings, a muscle is crushed, potassium (K+) is released and then increased in the blood. Hyperkalemia means extracellular potassium is NOT as low, which also means that the difference between extra- and intra- cellular potassium (K+) is less. There will be less diffusion of K+ through the K+ channel, resting membrane potential decreases, and the stability of the cardiac muscle cell decreases, causing arrhythmia.
Challenge Quiz
When a muscle is crushed, K+ in blood is increased decreased , and in cardiac muscle cells, diffusion of K+ through K+ channel is less more , resting membrane potential is less more , stability of the cell is less more , causing arrythmia.