「Nervous system/overview of neurons/Crush syndrome/effect of hyperkalemia on cardiac muscle」の版間の差分
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With more diffusion, the intracellular resting membrane negative potential increases, and with more intracellular resting membrane potential, the cell becomes more stable | With more diffusion, the intracellular resting membrane negative potential increases, and with more intracellular resting membrane potential, the cell becomes more stable | ||
When the legs are compressed for a long time, such as in earthquake-destroyed buildings, a muscle is crushed, | When the legs are compressed for a long time, such as in earthquake-destroyed buildings, a muscle is crushed, potassium (K+) is released and then increased in the blood. Hyperkalemia means extracellular potassium is NOT as low, which also means that the difference between extra- and intra- cellular potassium (K+) is less. | ||
There will be less diffusion of K+ through the K+ channel, resting membrane potential decreases, and the stability of the cardiac muscle cell, decreases, causing arrhythmia. | There will be less diffusion of K+ through the K+ channel, resting membrane potential decreases, and the stability of the cardiac muscle cell, decreases, causing arrhythmia. | ||
2014年6月6日 (金) 09:28時点における版
When a muscle is crushed, K+ in blood is increased, and in cardiac muscle cells, diffusion of K+ through K+ channel is less, resting membrane potential is less, stability of the cell is less, causing arrythmia. |
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Both the high intra-cellular potassium (K+) and low extra-cellular potassium (K+) bring about the difference, which is the driving force of the diffusion of potassium ion (K+) through channel. With more diffusion, the intracellular resting membrane negative potential increases, and with more intracellular resting membrane potential, the cell becomes more stable
When the legs are compressed for a long time, such as in earthquake-destroyed buildings, a muscle is crushed, potassium (K+) is released and then increased in the blood. Hyperkalemia means extracellular potassium is NOT as low, which also means that the difference between extra- and intra- cellular potassium (K+) is less. There will be less diffusion of K+ through the K+ channel, resting membrane potential decreases, and the stability of the cardiac muscle cell, decreases, causing arrhythmia.
Challenge Quiz
When a muscle is crushed, K+ in blood is increased. decreased , and in cardiac muscle cells, diffusion of K+ through K+ channel is less. more , resting membrane potential is less. more , stability of the cell is less. more , causing arrythmia.