「Endocrinology/HormonesWithoutMuchPituitaryRole/GlucagonAndInsuliln/Insulin/ControlBasic/Fasting」の版間の差分

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{{Point|When blood glucose is decreased, negative feedback inhibits insuliln(synthesis, secretion, and blood concentration).}}
{{Point|When blood glucose is decreased, negative feedback inhibits insulin (synthesis, secretion, and concentration in blood).}}




[[メディア:insulin-fast.mp4|動画と音声での説明]]
[[メディア:insulin-fast.mp4|動画と音声での説明]]
[[ファイル:InsulinBaselineJpn.jpg|left|500px]]
[[ファイル:InsulinBaselineJpn.jpg|left|500px]]
(Synthesis, secretion, and blood concentration of) insuliln decreases blood glucose. Insuliln has a certain (baseline) amount of synthesis, secretion, blood concentration, and blood glucose-increasing effect before fasting.
(Synthesis, secretion, and concentration in blood of) insulin decreases blood glucose. Before fast, insulin has certain levels of synthesis, secretion, concentration in blood, and blood glucose-decreasing effect.
 
 
インスリン（の生成、内分泌、血中濃度）は血糖を低下させます。インスリンは絶食の前（ベースライン）にもある一定量の生成、内分泌、血中濃度、血糖低下作用があります。
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[[ファイル:insulin-fast.jpg|left|500px]]
[[ファイル:insulin-fast.jpg|left|500px]]
① Subject had fasted. Blood glucose is decreased due to the fasting. Insuliln (synthesis, secretion, and blood concentration) decreases blood glucose. These are in the <font color="#ff0000">same direction (red)</font>.
① Subject had fasted. Blood glucose is decreased due to the fasting. Insulin (synthesis, secretion, and concentration in blood) decreases blood glucose. These are in the <font color="#ff0000">same direction (red)</font>.
 




① 絶食しました。絶食により血糖は低下します。インスリン（の生成、内分泌、血中濃度）は血糖を低下させます。これらは<font color="#ff0000">同じ方向（赤）</font>です。
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[[ファイル:グルカゴン・インスリン08.jpg|left|500px]]
[[ファイル:グルカゴン・インスリン08.jpg|left|500px]]
② Since these are in the <font color="#ff0000">same direction (red)</font>, negative feedback <font color="#00f">inhibits (blue)</font> insuliln (synthesis, secretion, and blood concentration). Because of this, the blood glucose-increasing effect of glucagon weakens, and the decrease in blood glucose (blue downward unfilled arrow) disappears (decreased blood glucose increases to the baseline).
② Since these are in the <font color="#ff0000">same direction (red)</font>, negative feedback <font color="#00f">inhibits (blue)</font> insulin (synthesis, secretion, and concentration in blood). Because of this, the blood glucose-decreasing effect of glucagon weakens, and the decrease in blood glucose (blue downward unfilled arrow) disappears (decreased blood glucose increases to the baseline).
 


② これらは<font color="#ff0000">同じ方向（赤）</font>なので、負のフィードバックはインスリン（の生成、内分泌、血中濃度）を<font color="#00f">低下（青）</font>させます。これにより、インスリンの血糖低下作用が減弱し、血糖の低下（青い下向きの白抜き矢印）が消えます。（低下していた血糖はベースラインの血糖へ向けて上昇します）。
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Like, when room temperature is decreased (winter), cooler (function) is decreased, this is also <font color="#ff0000">red</font>→<font color="#00f">blue</font> negative feedback.
Like, when room temperature is decreased (winter), cooler (function) is decreased, this is also <font color="#ff0000">red</font>→<font color="#00f">blue</font> negative feedback.
室温が低下した時（冬）にクーラー（の機能）を低下させるのと同様、これも<font color="#ff0000">赤</font>→<font color="#00f">青</font>の負のフィードバックです。


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31行目: 25行目:
//LEVEL:3  
//LEVEL:3  
//RAND  
//RAND  
絶食により血糖は{~上昇~=低下}し、インスリン（の生成、内分泌、血中濃度）は血糖を{~上昇~=低下}させる。これらは{~=同じ方向~逆の方向}であるので、負のフィードバックはインスリンを{~=低下~亢進}させる。この調節により、血糖の最初の変化は消える、すなわち血糖は(ベースラインへ向けて){~=上昇~低下}する。
Blood glucose is {~increased~=decreased} due to the fasting, insulin (synthesis, secretion, and concentration in blood{~increases~=decreases} blood glucose. Since these are in the {~=same direction~opposite direction}, negative feedback {~=inhibits~facilitates} insulin. Because of this, the initial transition dissapears and the blood glucose {~=increases~decreases} (towards the baseline).
 


//LEVEL:2
//LEVEL:2
//RAND  
//RAND  
血糖が低下した時、負のフィードバックはインスリン（の生成、内分泌、血中濃度）を{~亢進~=低下}させる。
When blood glucose is decreased, negative feedback {~facilitates~=inhibits} insulin (synthesis, secretion, and concentration in blood).
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2024年2月27日 (火) 23:36時点における最新版

POINT!
When blood glucose is decreased, negative feedback inhibits insulin (synthesis, secretion, and concentration in blood).


動画と音声での説明

InsulinBaselineJpn.jpg

(Synthesis, secretion, and concentration in blood of) insulin decreases blood glucose. Before fast, insulin has certain levels of synthesis, secretion, concentration in blood, and blood glucose-decreasing effect.


Insulin-fast.jpg

① Subject had fasted. Blood glucose is decreased due to the fasting. Insulin (synthesis, secretion, and concentration in blood) decreases blood glucose. These are in the same direction (red).



グルカゴン・インスリン08.jpg

② Since these are in the same direction (red), negative feedback inhibits (blue) insulin (synthesis, secretion, and concentration in blood). Because of this, the blood glucose-decreasing effect of glucagon weakens, and the decrease in blood glucose (blue downward unfilled arrow) disappears (decreased blood glucose increases to the baseline).


Like, when room temperature is decreased (winter), cooler (function) is decreased, this is also red→blue negative feedback.


Challenge Quiz

1.

Blood glucose is increased decreased due to the fasting, insulin (synthesis, secretion, and concentration in blood increases decreases blood glucose. Since these are in the same direction opposite direction , negative feedback inhibits facilitates insulin. Because of this, the initial transition dissapears and the blood glucose increases decreases (towards the baseline).

2.

When blood glucose is decreased, negative feedback facilitates inhibits insulin (synthesis, secretion, and concentration in blood).

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