「SHolroydAtWeilCornellMedQatar/Urology/Kidney/Tubules/WaterChannels/EffectOfIncrease」の版間の差分
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{{Point| With an increase in the number of water channels, water reabsorption from the tubule increases. | {{Point| With an increase in the number of water channels, water reabsorption from the tubule increases. }} | ||
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[[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | [[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | ||
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[[ファイル:WaterChannelsBaseLine-Eng.jpg|left|500px]] | [[ファイル:WaterChannelsBaseLine-Eng.jpg|left|500px]] | ||
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[[メディア:WaterChannelsBaseLine-Eng.mp4|video prior to the increase in vasopressin (ADH)]]<br> | [[メディア:WaterChannelsBaseLine-Eng.mp4|video prior to the increase in vasopressin (ADH)]]<br> | ||
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Prior to the number of water channels increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume. | Prior to the number of water channels increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume. | ||
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Step 1: Suppose that the number of water channels increases. | Step 1: Suppose that the number of water channels increases. | ||
Step 2: With the increase in the number of water channels, water reabsorption from the tubule increases. | Step 2: With the increase in the number of water channels, water reabsorption from the tubule increases. | ||
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[[メディア:WaterChannelsEffectOfIncrease-3Eng.mp4|video showing the changes in plasma and urine after the increase in vasopressin (ADH)]]<br> | [[メディア:WaterChannelsEffectOfIncrease-3Eng.mp4|video showing the changes in plasma and urine after the increase in vasopressin (ADH)]]<br> | ||
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Step 3: With the increase in water reabsorption, diluted (hypotonic) solution enters the plasma. This decreases plasma osmolarity (diluted, hypotonic). Because diluted (hypotonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has an increased osmolarity (concentrated, hypertonic). Also, with the increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes concentrated and decreases in volume. | Step 3: With the increase in water reabsorption, diluted (hypotonic) solution enters the plasma. This decreases plasma osmolarity (diluted, hypotonic). Because diluted (hypotonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has an increased osmolarity (concentrated, hypertonic). Also, with the increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes concentrated and decreases in volume. | ||
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//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With an increase in the number of water channels, water reabsorption from the tubule {~=increases~decreases}. | With an increase in the number of water channels, water reabsorption from the tubule {~=increases~decreases}. | ||
//LEVEL: | //LEVEL:3 | ||
//RAND | //RAND | ||
With an increase in the number of water channels, urine volume {~increases~=decreases}. | With an increase in the number of water channels, urine volume {~increases~=decreases}. | ||
//LEVEL: | //LEVEL:3 | ||
//RAND | //RAND | ||
With an increase in the number of water channels, urine osmolarity {~=increases~decreases}. | With an increase in the number of water channels, urine osmolarity {~=increases~decreases}. | ||
//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With an increase in the number of water channels, plasma osmolarity {~increases~=decreases}. | With an increase in the number of water channels, plasma osmolarity {~increases~=decreases}. | ||
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2020年4月17日 (金) 12:07時点における最新版
| With an increase in the number of water channels, water reabsorption from the tubule increases. |
Prior to the number of water channels increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume.
Step 1: Suppose that the number of water channels increases.
Step 2: With the increase in the number of water channels, water reabsorption from the tubule increases.
Step 3: With the increase in water reabsorption, diluted (hypotonic) solution enters the plasma. This decreases plasma osmolarity (diluted, hypotonic). Because diluted (hypotonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has an increased osmolarity (concentrated, hypertonic). Also, with the increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes concentrated and decreases in volume.
Challenge Quiz
With an increase in the number of water channels, water reabsorption from the tubule increases decreases .
With an increase in the number of water channels, urine volume increases decreases .
With an increase in the number of water channels, urine osmolarity increases decreases .
With an increase in the number of water channels, plasma osmolarity increases decreases .