「Endocrinology/VasopressinADH/ControlToWaterIntake/basic」の版間の差分

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{{Point|With sweating, the (blue→red) negative feedback facilitates (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).}}
{{Point|With water intake, the (red→blue) negative feedback decreases (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).}}
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[[ファイル:WaterIntakeBeforeBasicFeedbackToADH.jpg|left|500px]]
[[ファイル:WaterIntakeBeforeBasicFeedbackToADH-Eng.jpg|left|500px]]


① Sweating increases plasma osmolarity, and reabsorption (through the water channels, which are increased by vasopressin, ADH) decreases plasma osmolarity. The effects of these two are in the <font color="#00f">opposite direction (blue)</font>.
1st star (illustration): Subject had water. With water intake, plasma osmolarity decreases.(Synthesis, secretion, and concentration in blood of )vasopressin (ADH) (increases water channels.  Water channels increase water reabsorption.  Water reabsorption) decreases plasma osmolarity.<br> ①(illustration): These are in the <font color="#ff0000">same direction (red)</font>.
 
<br style="clear:both;" />
[[ファイル:WaterIntakeDuringBasicFeedbackToADH.jpg|left|500px]]
[[ファイル:WaterIntakeDuringBasicFeedbackToADH-Eng.jpg|left|500px]]


② Since the effects of these two are in the <font color="#00f">opposite direction (blue)</font>, negative feedback <font color="#ff0000">facilitates (red)</font> (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH)This increases the number of water channels and the reabsorption of water.  The plasma osmolarity-decreasing effect of the reabsorption increases, and the plasma osmolarity becomes adequate.  
(illustration): Since these are in the <font color="#ff0000">same direction (red)</font>, negative feedback <font color="#00f">decreases (blue)</font> (synthesis, secretion, and concentration in blood of vasopressin (ADH).<br>
<br>
With the decrease in (the synthesis, secretion, and concentration in blood of) vasopressin (ADH), (water channel-increasing effect is weakened, and water channels are decreasedWith the decrease in water channels, water reabsorption-increasing effect is weakened, and water absorption is decreasedWith the decrease in water reaborption), plasma osmolarity-decreasing effect is weakened.<br>
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Because of this control, the decreased plasma osmolarity decreases (towards that before water intake).
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Namely, the initial change (the decrease in plasma osmolarity) increases (blue downward unfilled arrow disappears).<br>
<br style="clear:both;" />  
<br style="clear:both;" />  
Similar to cooler (function) being increased when room temperature is increased (winter),  this also is <font color="#ff0000">red</font>→<font color="#00f">blue</font> negative feedback.


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//LEVEL:2  
//LEVEL:2  
//RAND
//RAND
Sweating {~=increases~decreases} plasma osmolarity, and reabsorption (through the water channels, which are increased by vasopressin, ADH) {~increases~=decreases} plasma osmolarity.  Since these effects are in the {~same~=opposite} direction, with sweating, negative feedback {~=facilitates~inhibits} (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).
Water intake {~increases~=decreases} plasma osmolarity, and water reabsorption (through the water channels, which are increased by vasopressin, ADH) {~increases~=decreases} plasma osmolarity.  Since these effects are in the {~=same~opposite} direction, negative feedback {~increases~=decreases} (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).
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2024年4月1日 (月) 12:23時点における最新版

POINT!
WaterIntakeBeforeBasicFeedbackToADH-Eng.jpg

1st star (illustration): Subject had water. With water intake, plasma osmolarity decreases.(Synthesis, secretion, and concentration in blood of )vasopressin (ADH) (increases water channels. Water channels increase water reabsorption. Water reabsorption) decreases plasma osmolarity.
①(illustration): These are in the same direction (red).

WaterIntakeDuringBasicFeedbackToADH-Eng.jpg

②(illustration): Since these are in the same direction (red), negative feedback decreases (blue) (synthesis, secretion, and concentration in blood of vasopressin (ADH).

With the decrease in (the synthesis, secretion, and concentration in blood of) vasopressin (ADH), (water channel-increasing effect is weakened, and water channels are decreased. With the decrease in water channels, water reabsorption-increasing effect is weakened, and water absorption is decreased. With the decrease in water reaborption), plasma osmolarity-decreasing effect is weakened.

Because of this control, the decreased plasma osmolarity decreases (towards that before water intake).

Namely, the initial change (the decrease in plasma osmolarity) increases (blue downward unfilled arrow disappears).

Similar to cooler (function) being increased when room temperature is increased (winter), this also is redblue negative feedback.

Challenge Quiz

1.

Water intake increases decreases plasma osmolarity, and water reabsorption (through the water channels, which are increased by vasopressin, ADH) increases decreases plasma osmolarity. Since these effects are in the same opposite direction, negative feedback increases decreases (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).