「SHolroydAtWeilCornellMedQatar/Urology/Kidney/Tubules/WaterChannels/EffectOfDecrease」の版間の差分
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{{Point| With a decrease in the number of water channels, water reabsorption from the tubule decreases. | {{Point| With a decrease in the number of water channels, water reabsorption from the tubule decreases. }} | ||
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[[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | [[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | ||
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[[メディア:WaterChannelsBaseLine-Eng.mp4|video prior to the decrease in vasopressin (ADH)]]<br> | [[メディア:WaterChannelsBaseLine-Eng.mp4|video prior to the decrease in vasopressin (ADH)]]<br> | ||
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Prior to the number of water channels decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume. | Prior to the number of water channels decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume. | ||
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[[メディア:WaterChannelsEffectOfDecreasing-2Eng.mp4|video just after the decrease in vasopressin (ADH)]]<br> | [[メディア:WaterChannelsEffectOfDecreasing-2Eng.mp4|video just after the decrease in vasopressin (ADH)]]<br> | ||
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Step 1: Suppose that the number of water channels decreases. Step 2: With the decrease in the number of water channels, water reabsorption from the tubule decreases. | Step 1: Suppose that the number of water channels decreases. Step 2: With the decrease in the number of water channels, water reabsorption from the tubule decreases. | ||
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[[メディア:WaterChannelsEffectOfDecreasing-3Eng.mp4|video showing the changes in plasma and urine after the decrease in vasopressin (ADH)]]<br> | [[メディア:WaterChannelsEffectOfDecreasing-3Eng.mp4|video showing the changes in plasma and urine after the decrease in vasopressin (ADH)]]<br> | ||
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Step 3:With the decrease in water reabsorption, concentrated (hypertonic) solution enters the plasma. This increases plasma osmolarity (concentrated, hypertonic). Because concentrated (hypertonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has decreased osmolarity (diluted, hypotonic). Also, with the decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes diluted and increases in volume. | Step 3:With the decrease in water reabsorption, concentrated (hypertonic) solution enters the plasma. This increases plasma osmolarity (concentrated, hypertonic). Because concentrated (hypertonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has decreased osmolarity (diluted, hypotonic). Also, with the decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes diluted and increases in volume. | ||
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//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With a decrease in the number of water channels, water reabsorption from the tubule {~increases~=decreases}. | With a decrease in the number of water channels, water reabsorption from the tubule {~increases~=decreases}. | ||
//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With a decrease in the number of water channels, urine volume {~=increases~decreases}. | With a decrease in the number of water channels, urine volume {~=increases~decreases}. | ||
//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With a decrease in the number of water channels, urine osmolarity {~increases~=decreases}. | With a decrease in the number of water channels, urine osmolarity {~increases~=decreases}. | ||
//LEVEL:2 | //LEVEL:2 | ||
//RAND | //RAND | ||
With a decrease in the number of water channels, plasma osmolarity {~=increases~decreases}. | With a decrease in the number of water channels, plasma osmolarity {~=increases~decreases}. | ||
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2020年3月31日 (火) 10:23時点における版
| With a decrease in the number of water channels, water reabsorption from the tubule decreases. |
Prior to the number of water channels decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume.
Step 1: Suppose that the number of water channels decreases. Step 2: With the decrease in the number of water channels, water reabsorption from the tubule decreases.
Step 3:With the decrease in water reabsorption, concentrated (hypertonic) solution enters the plasma. This increases plasma osmolarity (concentrated, hypertonic). Because concentrated (hypertonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has decreased osmolarity (diluted, hypotonic). Also, with the decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes diluted and increases in volume.
Challenge Quiz
With a decrease in the number of water channels, water reabsorption from the tubule increases decreases .
With a decrease in the number of water channels, urine volume increases decreases .
With a decrease in the number of water channels, urine osmolarity increases decreases .
With a decrease in the number of water channels, plasma osmolarity increases decreases .