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{{Point| With | {{Point| With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels and water reabsorption decrease. These increse plasma osmolarity and urine volume, and also decrease urine osmolarity.}} | ||
[[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | [[メディア:6-ADHcontrol-sweat.mp4|narrated video explanation]] | ||
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[[ファイル:ADHbaseline-Eng.jpg|left|500px]] | [[ファイル:ADHbaseline-Eng.jpg|left|500px]] | ||
[[メディア:ADHbaseline-Eng.mp4|video prior to | [[メディア:ADHbaseline-Eng.mp4|video prior to an decrease in vasopressin (ADH)]]<br> | ||
Prior to vasopressin (ADH) decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and volumes. | Prior to vasopressin (ADH) decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and volumes. | ||
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[[ファイル:ADHEffectOfDecreasing-2Eng.jpg|left|500px]] | [[ファイル:ADHEffectOfDecreasing-2Eng.jpg|left|500px]] | ||
[[メディア:ADHEffectOfDecreasing-2Eng.mp4|video just after | [[メディア:ADHEffectOfDecreasing-2Eng.mp4|video just after an decrease in vasopressin (ADH)]]<br> | ||
Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) decreases.<br> | Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) decreases.<br> | ||
Step 2: The water channel-increasing effect of vasopressin (ADH) decreases | Step 2: The water channel-increasing effect of vasopressin (ADH) becomes weaker, which decreases the number of water channels. This decreases the reabsorption of water by the kidney. | ||
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//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
The effect of | The effect of decrease in vasopressin (anti-diuretic hormone, ADH) is {uterine smooth muscle relaxation~=an increase in plasma osmolarity}. | ||
//LEVEL:3 | //LEVEL:3 | ||
//RAND | //RAND | ||
The effect of | The effect of decrease in vasopressin (anti-diuretic hormone, ADH) is {~=an increase~a decrease} the plasma osmolarity . | ||
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2019年8月31日 (土) 12:39時点における版
| With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels and water reabsorption decrease. These increse plasma osmolarity and urine volume, and also decrease urine osmolarity. |
video prior to an decrease in vasopressin (ADH)
Prior to vasopressin (ADH) decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and volumes.
video just after an decrease in vasopressin (ADH)
Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) decreases.
Step 2: The water channel-increasing effect of vasopressin (ADH) becomes weaker, which decreases the number of water channels. This decreases the reabsorption of water by the kidney.
video showing the changes in plasma and urine after the decrease in vasopressin (ADH)
Step 3: The ratio of Na+ to water entering the plasma due to reabsorption increases. This increases plasma osmolarity (hypertonic). Because a higher ratio of Na+ to water leaves the tubule due to reabsorption, the fluid remaining in the tubule has a lower osmolarity (hypotonic). Also, with a decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes less concentrated (hypotonic) and higher in volume.
Challenge Quiz
With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels in the kidney increases decreases .
With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), water reabsorption by the kidney increases decreases .
With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine volume increases decreases .
With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine osmolarity increases decreases .
With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), plasma osmolarity increases decreases .
The effect of decrease in vasopressin (anti-diuretic hormone, ADH) is uterine smooth muscle relaxation an increase in plasma osmolarity .
The effect of decrease in vasopressin (anti-diuretic hormone, ADH) is an increase a decrease the plasma osmolarity .