「SHolroydAtWeilCornellMedQatar/Endocrinology/VasopressinADH/EffectOfIncrease」の版間の差分

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[[メディア:ADHEffectOfIncreasing-3Eng.mp4|video showing the changes in plasma and urine after the increase in vasopressin (ADH)]]<br>
[[メディア:ADHEffectOfIncreasing-3Eng.mp4|video showing the changes in plasma and urine after the increase in vasopressin (ADH)]]<br>
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Step 3: With the increase in water reabsorption, diluted (hypotonic) solution enters the plasma. This decreases plasma osmolarity (diluted, hypotonic). Because diluted (hypotonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has an increased osmolarity (concentrated, hypertonic). Also, with the increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes concentrated and decreases in volume. <br style="clear:both;" />
Step 3: With the increase in water reabsorption, diluted (hypotonic) solution enters the plasma. This decreases plasma osmolarity (diluted, hypotonic). Because diluted (hypotonic) solution leaves the tubule due to water reabsorption, the fluid remaining in the tubule has an increased osmolarity (concentrated, hypertonic). Also, with the increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes concentrated and decreases in volume. <br style="clear:both;" />
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2020年3月17日 (火) 14:11時点における版

POINT!


ADHbaseline-Eng.jpg

Prior to vasopressin (ADH) increasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume.

ADHEffectOfIncreasing-2Eng.jpg

Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) increases.
Step 2: The water channel-increasing effect of vasopressin (ADH) becomes stronger, which increases the number of water channels. This increases the water reabsorption from the tubule.

ADHEffectOfIncreasing-3Eng.jpg

Step 3: With the increase in water reabsorption, diluted (hypotonic) solution enters the plasma. This decreases plasma osmolarity (diluted, hypotonic). Because diluted (hypotonic) solution leaves the tubule due to water reabsorption, the fluid remaining in the tubule has an increased osmolarity (concentrated, hypertonic). Also, with the increase in water reabsorption, there is less water remaining in the tubule. Overall, the urine becomes concentrated and decreases in volume.

Challenge Quiz

1.

With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels in the tubule increases decreases .

2.

With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), water reabsorption from the tubule increases decreases .

3.

With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine volume increases decreases .

4.

With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine osmolarity increases decreases .

5.

With an increase in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), plasma osmolarity increases decreases .

6.

The effect of increase in vasopressin (anti-diuretic hormone, ADH) is uterine smooth muscle contration a decrease in plasma osmolarity .

7.

The effect of increase in vasopressin (anti-diuretic hormone, ADH) is an increase a decrease in plasma osmolarity.