「SHolroydAtWeilCornellMedQatar/Endocrinology/VasopressinADH/EffectOfDecrease」の版間の差分

提供:一歩一歩
ナビゲーションに移動 検索に移動
編集の要約なし
編集の要約なし
20行目: 20行目:
[[ファイル:ADHEffectOfDecreasing-3Eng.jpg|left|500px]]
[[ファイル:ADHEffectOfDecreasing-3Eng.jpg|left|500px]]
[[メディア:ADHEffectOfDecreasing-3Eng.mp4|video showing the changes in plasma and urine after the decrease in vasopressin (ADH)]]<br>
[[メディア:ADHEffectOfDecreasing-3Eng.mp4|video showing the changes in plasma and urine after the decrease in vasopressin (ADH)]]<br>
Step 3: With decrease in water reabsorption, thicker (hypertonic) solution enters the plasma. This increases plasma osmolarity. <br>  
Step 3: With decrease in water reabsorption, thicker (hypertonic) solution enters the plasma. This increases plasma osmolarity. <br>  
Because thicker (hypertonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has a lower osmolarity (hypotonic). Also, with the decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes less concentrated (hypotonic) and higher in volume.
Because thicker (hypertonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has a lower osmolarity (hypotonic). Also, with the decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes less concentrated (hypotonic) and higher in volume.
<br style="clear:both;" />
<br style="clear:both;" />

2019年9月16日 (月) 00:01時点における版

POINT!

narrated video explanation

ADHbaseline-Eng.jpg

video prior to a decrease in vasopressin (ADH)
Prior to vasopressin (ADH) decreasing (at baseline), we will make the assumption that the subject is in homeostasis with normal plasma and urine osmolarities (isotonic) and urine volume.

ADHEffectOfDecreasing-2Eng.jpg

video just after a decrease in vasopressin (ADH)
Step 1: Suppose that the synthesis, secretion, and blood concentration of vasopressin (ADH) decreases.
Step 2: The water channel-increasing effect of vasopressin (ADH) becomes weaker, which decreases the number of water channels. This decreases the reabsorption of water by the kidney.

ADHEffectOfDecreasing-3Eng.jpg

video showing the changes in plasma and urine after the decrease in vasopressin (ADH)
Step 3: With decrease in water reabsorption, thicker (hypertonic) solution enters the plasma. This increases plasma osmolarity.
Because thicker (hypertonic) solution leaves the tubule due to reabsorption, the fluid remaining in the tubule has a lower osmolarity (hypotonic). Also, with the decrease in water reabsorption, there is more water remaining in the tubule. Overall, the urine becomes less concentrated (hypotonic) and higher in volume.

Challenge Quiz

1.

With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), the number of water channels in the kidney increases decreases .

2.

With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), water reabsorption by the kidney increases decreases .

3.

With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine volume increases decreases .

4.

With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), urine osmolarity increases decreases .

5.

With a decrease in the synthesis, secretion, and blood concentration of vasopressin (anti-diuretic hormone, ADH), plasma osmolarity increases decreases .

6.

The effect of decrease in vasopressin (anti-diuretic hormone, ADH) is uterine smooth muscle relaxation an increase in plasma osmolarity .

7.

The effect of decrease in vasopressin (anti-diuretic hormone, ADH) is an increase a decrease the plasma osmolarity .