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[[ファイル:SweatingBeforeBasicFeedbackToADH-Eng.jpg|left|500px]]
[[ファイル:SweatingBeforeBasicFeedbackToADH-Eng.jpg|left|500px]]


① Sweating increases plasma osmolarity (concentrated, hypertonic), and water reabsorption (through the water channels, which are increased by vasopressin, ADH) decreases plasma osmolarity. These effects are in the <font color="#00f">opposite direction (blue)</font>.
1st star (illustration): Subject sweated.  With sweating, plasma osmolarity increases.  (Synthesis, secretion, and concentration in blood of )vasopressin (ADH) (increases water channels.  Water channels increase water reabsorption.  Water reabsorption) decreases plasma osmolarity.<br>
①(illustration): These are in the <font color="#00f">opposite direction (blue)</font>.
<br style="clear:both;" />  
<br style="clear:both;" />  
[[ファイル:SweatingDuringBasicFeedbackToADH-Eng.jpg|left|500px]]
[[ファイル:SweatingDuringBasicFeedbackToADH-Eng.jpg|left|500px]]


② Since these effects are in the <font color="#00f">opposite direction (blue)</font>, negative feedback <font color="#ff0000">increases (red)</font> (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH)This increases the number of water channels and the water reabsorptionThe plasma osmolarity-decreasing effect of the water reabsorption becomes stronger.  This will lead to a reverse in the increased plasma osmolarity (concentrated, hypertonic) produced by sweating, decreasing it towards normal (baseline, isotonic) osmolarity.  
(illustration): Since these are in the <font color="#00f">opposite direction (blue)</font>, negative feedback <font color="#ff0000">increases (red)</font> (synthesis, secretion, and concentration in blood of vasopressin (ADH).<br> 
<br>
With the increase in (the synthesis, secretion, and concentration in blood of)vasopressin (ADH), (water channel-increasing effect is strengthened, and water channels are increasedWith the increase in water channels, water reabsorption-increasing effect is strengthened, and water absorption is increasedWith the increase in water reaborption), plasma osmolarity-decreasing effect is strengthened.<br>
<br>
Because of this control, the increased plasma osmolarity decreases (towards that before sweating).
<br>
<br>
Namely, the initial change (the increase in plasma osmolarity) decreases (red upward unfilled arrow disappears).<br>
<br style="clear:both;" />  
<br style="clear:both;" />  
Similar to cooler (function) being increased when room temperature is increased (summer),  this also is <font color="#00f">blue</font>→<font color="#ff0000">red</font> negative feedback.


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2024年4月1日 (月) 10:09時点における版

POINT!
SweatingBeforeBasicFeedbackToADH-Eng.jpg

1st star (illustration): Subject sweated. With sweating, plasma osmolarity increases. (Synthesis, secretion, and concentration in blood of )vasopressin (ADH) (increases water channels. Water channels increase water reabsorption. Water reabsorption) decreases plasma osmolarity.
①(illustration): These are in the opposite direction (blue).

SweatingDuringBasicFeedbackToADH-Eng.jpg

②(illustration): Since these are in the opposite direction (blue), negative feedback increases (red) (synthesis, secretion, and concentration in blood of vasopressin (ADH).

With the increase in (the synthesis, secretion, and concentration in blood of)vasopressin (ADH), (water channel-increasing effect is strengthened, and water channels are increased. With the increase in water channels, water reabsorption-increasing effect is strengthened, and water absorption is increased. With the increase in water reaborption), plasma osmolarity-decreasing effect is strengthened.

Because of this control, the increased plasma osmolarity decreases (towards that before sweating).

Namely, the initial change (the increase in plasma osmolarity) decreases (red upward unfilled arrow disappears).

Similar to cooler (function) being increased when room temperature is increased (summer), this also is bluered negative feedback.

Challenge Quiz

1.

Sweating increases decreases plasma osmolarity, and water reabsorption (through the water channels, which are increased by vasopressin, ADH) increases decreases plasma osmolarity. Since these effects are in the same opposite direction, negative feedback increases decreases (the synthesis, secretion, and blood concentration of) vasopressin (anti-diuretic hormone, ADH).