Endocrinology/HormonesWithoutMuchPituitaryRole/GlucagonAndInsuliln/Insulin/ControlBasic/Fasting

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2023年8月2日 (水) 11:31時点におけるAdmin (トーク | 投稿記録)による版
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POINT!


動画と音声での説明

InsulinBaselineJpn.jpg

(Synthesis, secretion, and blood concentration of) insuliln decreases blood glucose. Insuliln has a certain (baseline) amount of synthesis, secretion, blood concentration, and blood glucose-increasing effect before fasting.


Insulin-fast.jpg

① Subject had fasted. Blood glucose is decreased due to the fasting. Insuliln (synthesis, secretion, and blood concentration) decreases blood glucose. These are in the same direction (red).



グルカゴン・インスリン08.jpg

② Since these are in the same direction (red), negative feedback inhibits (blue) insuliln (synthesis, secretion, and blood concentration). Because of this, the blood glucose-increasing effect of glucagon weakens, and the decrease in blood glucose (blue downward unfilled arrow) disappears (decreased blood glucose increases to the baseline).


Like, when room temperature is decreased (winter), cooler (function) is decreased, this is also redblue negative feedback.


Challenge Quiz

1.

Blood glucose is increased decreased due to the fasting, insuliln (synthesis, secretion, and blood concentration increases decreases blood glucose. Since these are in the same direction opposite direction , negative feedback inhibits facilitates insuliln. Because of this, the initial transition dissapears and the blood glucose increases decreases (towards the baseline).

2.

When blood glucose is decreased, negative feedback facilitates inhibits insuliln (synthesis, secretion, and blood concentration).